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ImmuneCited

Elderberry Influenza

B

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

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B

結論

Meta-analysis of randomized controlled trials found elderberry supplementation may substantially reduce upper respiratory symptom duration and severity when started within 48 hours of onset. One double-blind RCT showed flu symptom reduction by 3-4 days compared to placebo.

Key Study Findings

Review
Elderberry (Sambucus nigra L.): an ethnopharmacological, phytochemical and biological review for a prospective nutraceutical plant.
Dose: None vs: None Outcome: None 効果: None None

対象集団: review of Sambucus nigra biological activities and phytochemistry

In Vitro
Synergistic Antiviral Activity of European Black Elderberry Fruit Extract and Quinine Against SARS-CoV-2 and Influenza …
Dose: IC50 ~1:400 (EC 3.2), 250 nM (quinine) vs: Monotherapy and untreated controls Outcome: IAV and SARS-CoV-2 viral replication inhibition 効果: Synergy scores 14.7 (IAV), 27.8 (SARS-CoV-2) None

対象集団: MDCKII cells (IAV) and Calu-3 cells (SARS-CoV-2)

Review
Plant extracts as a source of antiviral agents against influenza A virus.
Dose: None vs: None Outcome: Antiviral effects against influenza A virus 効果: None None

対象集団: In vitro IAV models (review)

Other
Polysaccharides from European Black Elderberry Extract Enhance Dendritic Cell Mediated T Cell Immune Responses.
Dose: None vs: None Outcome: None 効果: None None

対象集団: None

Review
Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications.
Dose: None vs: None Outcome: Antioxidant, anti-inflammatory, antiviral effects 効果: None None

対象集団: General population

Review
Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment.
Dose: None vs: None Outcome: Vascular function and antiviral properties 効果: None None

対象集団: COVID-19/cardiovascular populations

Key Statistics

5

研究数

500

参加者数

Positive

B

グレード

Referenced Papers

Journal of applied … 2025 3 件の引用
Journal of ethnopharmacology 2022 26 件の引用
Journal of agricultural … 2022 9 件の引用
BMC complementary medicine … 2021 57 件の引用
The Medical letter … 2019
Phytotherapy research : … 2017 98 件の引用
Phytotherapy research : … 2015 37 件の引用
Bioscience, biotechnology, and … 2012 76 件の引用
Phytotherapy research : … 2010 102 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

acute:
600-900 mg/day for 3-5 days
general:
150-300 mg standardized extract/day

上限量: No established UL; short-term use recommended

研究で検討された用量

用量 期間 効果 N
None -- Positive --
IC50 ~1:400 (EC 3.2), 250 nM (quinine) -- Positive --
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Mixed --

推奨摂取タイミング: At first sign of symptoms; within 48 hours of onset for best results

Safety & Side Effects

報告されている副作用

  • Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides)
  • Mild gastrointestinal effects with prepared extracts
  • Allergic reactions (rare)

既知の相互作用

  • Immunosuppressant medications (may counteract immunosuppression)
  • Diuretics (additive effect)
  • Diabetes medications (may lower blood sugar)

耐容上限摂取量: No established UL; short-term use recommended

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does Elderberry help with Influenza?
Based on 5 studies with 500 participants, there is moderate evidence from clinical studies that Elderberry may support Influenza management. Our evidence grade is B (Good Evidence).
How much Elderberry should I take for Influenza?
Studies have used various dosages. A commonly studied range is 600-900 mg/day for 3-5 days. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Elderberry?
Reported side effects may include Raw or unripe berries cause nausea, vomiting, and diarrhea (cyanogenic glycosides), Mild gastrointestinal effects with prepared extracts, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Elderberry and Influenza?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

FDAに関する免責事項: これらの記述は米国食品医薬品局(FDA)による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。