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Vitamin D для Upper Respiratory Tract Infections

A

Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.

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Итог

Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.

Key Study Findings

Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None или: None Outcome: None Эффект: None None

Популяция: Elite/professional cyclists nutrition review

Systematic Review
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Dose: Disease-modifying agents (tolvaptan, etc.) или: Placebo or standard care Outcome: Kidney disease progression Эффект: None None

Популяция: Patients with ADPKD

Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals или: None Outcome: Immune response modulation in COVID-19 Эффект: None None

Популяция: COVID-19 patients with gut dysbiosis

Review
Revisiting Vitamin D Guidelines: A Critical Appraisal of the Literature.
Dose: 600-800 IU (DRI) or higher или: None Outcome: Skeletal and extra-skeletal health benefits Эффект: None None

Популяция: General population (guideline comparison)

Meta-Analysis n=5748
High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 …
Dose: 400 IU или: Placebo Outcome: None Эффект: None None

Популяция: Healthy adults

Case-Control 26.0 weeks
Vitamin D - An Elixir for Recurrent Upper Respiratory Tract Infection.
Dose: 98% или: control Outcome: None Эффект: None None

Популяция: None

Key Statistics

40

Исследования

30000

Участники

Positive

A

Оценка

Referenced Papers

Endocrine practice : … 2024 24 цитирований
The Cochrane database … 2024 1 цитирований
Dermatologic therapy 2022 42 цитирований
European archives of … 2019 14 цитирований
International journal of … 2018 165 цитирований
European journal of … 2016 93 цитирований
American journal of … 2016 45 цитирований
Journal of general … 2016 38 цитирований
Clinical infectious diseases … 2013 58 цитирований
Indian journal of … 2013 24 цитирований
Acta scientiarum polonorum. … 2012 11 цитирований
International journal of … 2011 49 цитирований
The Journal of … 2010 93 цитирований
Journal of the … 2010 11 цитирований
Clinical journal of … 2008 148 цитирований
International journal of … 2002 26 цитирований
Diseases of the … 2001 7 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
600-800 IU/day
immunesupport:
1,000-2,000 IU/day
deficiencycorrection:
4,000-5,000 IU/day (under medical supervision)

Верхний предел: 4,000 IU/day (100 mcg)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Mixed --
Disease-modifying agents (tolvaptan, etc.) -- Positive --
Probiotics, nutraceuticals -- Positive --
600-800 IU (DRI) or higher -- Positive --
400 IU -- Negative 5748
98% 26.0 weeks Mixed --
None -- Positive --
None -- Positive 50554

Лучшее время приёма: With a meal containing fat for better absorption

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Hypercalcemia at very high doses (nausea, vomiting, weakness)
  • Kidney stones with excessive long-term use
  • Constipation
  • Metallic taste

Известные взаимодействия

  • Thiazide diuretics (may increase risk of hypercalcemia)
  • Corticosteroids (reduce vitamin D absorption and metabolism)
  • Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
  • Statins (vitamin D may affect statin metabolism)

Допустимый верхний уровень потребления: 4,000 IU/day (100 mcg)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Vitamin D help with Upper Respiratory Tract Infections?
Based on 40 studies with 30,000 participants, there is strong evidence from multiple clinical trials that Vitamin D may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).
How much Vitamin D should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones with excessive long-term use, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Upper Respiratory Tract Infections?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 40 peer-reviewed studies with 30,000 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Upper Respiratory Tract Infections

Vitamin D для других состояний

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.