Vitamin D 관련 Upper Respiratory Tract Infections
ALancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.
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A
결론
Lancet 2025 meta-analysis shows vitamin D supplementation may help protect against acute respiratory infections, with strongest effects in individuals with baseline 25(OH)D levels below 25 nmol/L. Optimal protective dosing appears to be 400-1,200 IU/day rather than intermittent bolus dosing.
Key Study Findings
Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Elite/professional cyclists nutrition review
Systematic Review
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Dose: Disease-modifying agents (tolvaptan, etc.)
vs: Placebo or standard care
Outcome: Kidney disease progression
효과: None
None
대상 집단: Patients with ADPKD
Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals
vs: None
Outcome: Immune response modulation in COVID-19
효과: None
None
대상 집단: COVID-19 patients with gut dysbiosis
Review
Revisiting Vitamin D Guidelines: A Critical Appraisal of the Literature.
Dose: 600-800 IU (DRI) or higher
vs: None
Outcome: Skeletal and extra-skeletal health benefits
효과: None
None
대상 집단: General population (guideline comparison)
Meta-Analysis
n=5748
High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 …
Dose: 400 IU
vs: Placebo
Outcome: None
효과: None
None
대상 집단: Healthy adults
Case-Control
26.0 weeks
Vitamin D - An Elixir for Recurrent Upper Respiratory Tract Infection.
Dose: 98%
vs: control
Outcome: None
효과: None
None
대상 집단: None
Key Statistics
40
연구
30000
참여자
↑
Positive
A
등급
Referenced Papers
International journal of …
2025
2 인용
Endocrine practice : …
2024
24 인용
Nutrition reviews
2024
9 인용
Journal of translational …
2024
2 인용
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Systematic Review
The Cochrane database …
2024
1 인용
Indian journal of …
2023
Dermatologic therapy
2022
42 인용
Clinical nutrition (Edinburgh, …
2022
17 인용
Medicine and science …
2021
18 인용
Vitamin D and upper respiratory tract infections in young active males exposed to cold environments.
Other
Annals of agricultural …
2021
3 인용
The World Allergy …
2020
16 인용
Nutrients
2020
1 인용
The Pediatric infectious …
2019
15 인용
European archives of …
2019
14 인용
Association of the 25(OH) vitamin D status with upper respiratory tract infections morbidity in water sports elite athletes.
Observational
The Journal of …
2019
9 인용
Indian journal of …
2019
3 인용
International journal of …
2018
165 인용
International journal of …
2018
37 인용
The journal of …
2018
27 인용
JAMA
2017
131 인용
Public health nutrition
2017
6 인용
European journal of …
2016
93 인용
American journal of …
2016
45 인용
Journal of general …
2016
38 인용
International journal of …
2016
22 인용
Epidemiology and infection
2016
13 인용
[Changes in 25-hydroxyvitamin D3 level and its significance in children with Kawasaki disease].
Other
Zhongguo dang dai …
2016
5 인용
European journal of …
2016
BMC infectious diseases
2014
58 인용
Clinical infectious diseases …
2013
129 인용
Vitamin D3 supplementation and upper respiratory tract infections in a randomized, controlled trial.
RCT
Clinical infectious diseases …
2013
58 인용
Indian journal of …
2013
24 인용
Acta scientiarum polonorum. …
2012
11 인용
International journal of …
2011
49 인용
The Journal of …
2010
93 인용
Journal of the …
2010
11 인용
Archives of internal …
2009
975 인용
Clinical journal of …
2008
148 인용
International journal of …
2002
26 인용
Manometric study in Kearns-Sayre syndrome.
Case Report
Diseases of the …
2001
7 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 600-800 IU/day
- immunesupport:
- 1,000-2,000 IU/day
- deficiencycorrection:
- 4,000-5,000 IU/day (under medical supervision)
상한량: 4,000 IU/day (100 mcg)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| Disease-modifying agents (tolvaptan, etc.) | -- | Positive | -- |
| Probiotics, nutraceuticals | -- | Positive | -- |
| 600-800 IU (DRI) or higher | -- | Positive | -- |
| 400 IU | -- | Negative | 5748 |
| 98% | 26.0 weeks | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 50554 |
권장 복용 시간: With a meal containing fat for better absorption
Safety & Side Effects
보고된 부작용
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
- ⚠ Kidney stones with excessive long-term use
- ⚠ Constipation
- ⚠ Metallic taste
알려진 상호작용
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
일일 최대 섭취 허용량: 4,000 IU/day (100 mcg)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Vitamin D help with Upper Respiratory Tract Infections?
Based on 40 studies with 30,000 participants, there is strong evidence from multiple clinical trials that Vitamin D may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).
How much Vitamin D should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones with excessive long-term use, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Upper Respiratory Tract Infections?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 40 peer-reviewed studies with 30,000 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: Upper Respiratory Tract Infections
Vitamin D 다른 건강 상태에 대한 근거
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.