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Arginine pour Wound Healing and Immune Recovery

B

Arginine is a key immunonutrient alongside glutamine. Supplementation may enhance immune function in surgical patients and those with malnutrition by supporting nitric oxide-dependent pathogen killing by macrophages and tissue repair.

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B

En conclusion

Arginine is a key immunonutrient alongside glutamine. Supplementation may enhance immune function in surgical patients and those with malnutrition by supporting nitric oxide-dependent pathogen killing by macrophages and tissue repair.

Key Study Findings

Systematic Review n=1085
The Role of Glutamine and Arginine in Wound Healing of Pressure Ulcers: A Systematic Review.
Dose: None vs: Standard care or placebo Outcome: Wound healing time and wound size reduction Effet: Wound size reduction 18.6-98.2% over 2-20 weeks None

Population: Adults with pressure ulcers (15 studies)

Other
PRMT1-Mediated Arginine Methylation Promotes Corneal Epithelial Wound Healing via Epigenetic Regulation of ANXA3.
Dose: None vs: Wild-type mice and control HCECs Outcome: Corneal epithelial wound healing Effet: None None

Population: Murine corneal wound model and human corneal cells

In Vitro
Glucose-responsive multifunctional hydrogel incorporating GOx@ZIF-8 for NO/Zn2+-mediated antibacterial and pro-angiogenic diabetic wound healing.
Dose: None vs: None Outcome: Diabetic wound healing Effet: None None

Population: Diabetic wound model

In Vitro
Microenvironment-responsive MOF nanozymes armored cryogels promoted wound healing via rapid hemostasis, infection elimination and angiogenesis.
Dose: None vs: None Outcome: Diabetic wound healing Effet: None None

Population: Diabetic wound animal model

Other
Arginine-Nanoenzyme with Timely Angiogenesis for Promoting Diabetic Wound Healing.
Dose: None vs: Untreated diabetic wound controls Outcome: Diabetic wound healing via angiogenesis Effet: None None

Population: Diabetic ulcer mice model

Other
Liraglutide Promotes Diabetic Wound Healing via Myo1c/Dock5.
Dose: None vs: None Outcome: None Effet: None None

Population: Diabetes patients

Key Statistics

8

Études

600

Participants

Positive

B

Note

Referenced Papers

Advanced science (Weinheim, … 2024 15 citations
International journal of … 2022 77 citations
The Annals of … 2022 31 citations
Advances in experimental … 2021 206 citations
Journal of materials … 2021 36 citations
The Cochrane database … 2020 33 citations
Biological trace element … 2017 10 citations
Nutrition in clinical … 2016 42 citations
Nutrition in clinical … 2014 131 citations
Critical reviews in … 2012 969 citations
Current opinion in … 2008 240 citations
Plastic and reconstructive … 2006 98 citations
Nutrition in clinical … 2005 247 citations
The Journal of … 2004 181 citations
Mini reviews in … 2004 178 citations
Wound repair and … 2003 306 citations
The Surgical clinics … 2003 16 citations
Alternative medicine review … 2003
Advances in skin … 2001 10 citations
The American journal … 1994 91 citations
JPEN. Journal of … 1994 72 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:
2-3 g/day
immunesupport:
6-9 g/day

Limite supérieure : No established UL; typically tolerated at 20 g/day

Posologies étudiées dans la recherche

Posologie Durée Effet N
None -- Positive 1085
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive --
None -- Negative --
None -- Positive --

Moment optimal de prise : Between meals

Safety & Side Effects

Effets indésirables signalés

  • Gastrointestinal discomfort (bloating, diarrhea, cramps)
  • Gout exacerbation (increased uric acid production)
  • Blood pressure changes
  • Worsening of herpes outbreaks (arginine supports viral replication)

Interactions connues

  • Antihypertensive medications (additive blood pressure lowering)
  • PDE5 inhibitors like sildenafil (additive vasodilation)
  • Anticoagulants (may affect platelet function)
  • Potassium-sparing diuretics (arginine may increase potassium levels)

Apport maximal tolérable : No established UL; typically tolerated at 20 g/day

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Arginine help with Wound Healing and Immune Recovery?
Based on 8 studies with 600 participants, there is moderate evidence from clinical studies that Arginine may support Wound Healing and Immune Recovery management. Our evidence grade is B (Good Evidence).
How much Arginine should I take for Wound Healing and Immune Recovery?
Studies have used various dosages. A commonly studied range is 2-3 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Arginine?
Reported side effects may include Gastrointestinal discomfort (bloating, diarrhea, cramps), Gout exacerbation (increased uric acid production), Blood pressure changes, Worsening of herpes outbreaks (arginine supports viral replication). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Arginine and Wound Healing and Immune Recovery?
We rate the evidence as Grade B (Good Evidence). This rating is based on 8 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.